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Using two separate drugs to shed weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people that go through it one should err along the side of caution and let the FDA do its job and demand some study be done so your public is aware of the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies are in business to earn money and that they would say almost anything to keep people on his or her medications.

Researchers found that participants using this drug for the year, lost excess weight within 4 weeks and have kept the weight off throughout the 56 weeks of the study. Contrave is really a combination in the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs that are made up of several active ingredient, that might make them more efficient and safer.

Combo-pilling could be the newest fad or in addition to this the newest ahead under scrutiny and therefore it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is now popular is the fact that as of right now there aren't any long term prescription weightloss pills that have been approved by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be authorized by the FDA.

Seizures can be a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug also can raise blood pressure levels and pulse rate, and shouldn't be used in people with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must 't be used in patients with uncontrolled high blood pressure, and also by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients on the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.

"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.


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