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Contrave is looking very promising for anyone seeking a diet plan pill that work well. The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantages of the drug outweighs the potential risk of a possible boost in blood pressure.

Using two separate drugs to shed weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the people who go through it you ought to err assisting caution and let the FDA do its job and demand some study be done in order that the public understands the side effects and perils associated with the medications before we take them. Keep in mind that drug companies will be in business to earn money and that they would say everything to keep people on their own medications.

Researchers found out that participants using this drug to get a year, dropped a few pounds within 4 weeks and have kept the load off during the entire 56 weeks with the study. Contrave is often a combination with the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which are made up of more than one active ingredient, which may make them far better and safer.

Combo-pilling may be the newest fad or even better the newest into the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular could be the fact that at the time of right now there are not any long term prescription slimming capsules that have been authorized by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures certainly are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug also can raise hypertension and pulse rate, and really should not be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure level and heartrate and must 't be used in patients with uncontrolled high blood pressure, along with by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients on the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.

"There were no signs and symptoms of depression or suicidal thoughts in trial participants," said Fujioka.

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