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Physicians who treat opioid addiction likewise have the option of utilizing 'medication-assisted treatment', and the most common medications utilized in the treatment of opioid dependence today are methadone, naltrexone, and buprenorphine (Suboxone).

Using two separate drugs to shed weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the people that go through it you should err on the side of caution and allow the FDA do its job and demand some study be done so that the public recognizes the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies will be in business to make money and that they would say almost anything to keep people on his or her medications.

Researchers found out that participants using this drug for any year, lost excess weight within 4 weeks and have kept the load off during the entire 56 weeks from the study. Contrave is a combination in the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which are made up of multiple active ingredient, which may make them more potent and safer.

Combo-pilling could be the newest fad or even better the newest into the future under scrutiny and for that reason it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular is the fact that at the time of right now there aren't long term prescription weight loss supplements that have been approved by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be authorized by the FDA.

Seizures certainly are a side effect with Contrave and must not be taken in people with seizure disorders. The drug can also raise blood pressure levels and pulse rate, and really should not be used in those with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure level and heartbeat and must stop used in patients with uncontrolled high blood pressure levels, and also by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients towards the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.

"This is the first drug I'm conscious of that targets both appetite and reward centres inside the brain," he said.


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