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The Food and Drug Administration, FDA, has approved the drug Vivitrol for your treatment of opioid dependence according to a news release by them on 10-12-2010.

Using two separate drugs to lose weight naturally can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the people that go through it you should err on the side of caution and let the FDA do its job and demand some study be done so the public is aware of the side effects and risks of the medications before we drive them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on the medications.

Researchers found that participants investing in this drug for the year, dropped a few pounds within 4 weeks and have kept the extra weight off through the entire 56 weeks of the study. Contrave is often a combination with the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, that might make them more effective and safer.

Combo-pilling may be the newest fad or also the newest into the future under scrutiny and thus it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is now popular could be the fact that by right now there aren't any long term prescription weight loss supplements that have been licensed by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug also can raise blood pressure levels and heartrate, and must not be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure level and heartrate and must 't be used in patients with uncontrolled high blood pressure, as well as by a person with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients to the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

From a psychiatric perspective, evidence suggests that the ordinary neural mechanism for goal-directed behavior may be hijacked from the addiction, and malfunctions so that its ordinary functions are exaggerated and fixated on its object. An object produces a stimulus as well as the person engages in a "goal-directed behavioral response" that produces a "natural high"(Bostwick & Bucci, 2008).


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