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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight-loss in addition to a reduced-calorie diet and exercising.

Using two separate drugs to shed weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it one should err along the side of caution and let the FDA do its job and demand some study be done in order that the public recognizes the side effects and dangers of the medications before we take them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on his or her medications.

Researchers discovered that participants investing in this drug for a year, dropped a few pounds within a month and have kept the body weight off throughout the 56 weeks in the study. Contrave is often a combination with the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which can be made up of multiple active ingredient, which might make them more potent and safer.

Combo-pilling is the newest fad or even better the newest ahead under scrutiny and so it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular will be the fact that since right now there are no long term prescription diet pills that have been licensed by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug may also raise blood pressure and pulse rate, and shouldn't be used in individuals with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heart rate and must 't be used in patients with uncontrolled high blood pressure, and also by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients to the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.

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