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The FDA announced the approval of a new weight reduction drug on Sept. 11, 2014. The drug name is Contrave.

Using two separate drugs to shed weight can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the people that go through it you need to err along the side of caution and allow FDA do its job and demand some investigation be done so your public recognizes the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies come in business to earn money and that they would say anything to keep people on their own medications.

Researchers discovered that participants using this drug for a year, lost excess weight within four weeks and have kept the extra weight off through the 56 weeks with the study. Contrave is a combination from the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, that might make them more efficient and safer.

Combo-pilling could be the newest fad or also the newest ahead under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular will be the fact that as of right now there are not any long term prescription weightloss pills that have been licensed by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug also can raise blood pressure levels and heartrate, and mustn't be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise hypertension and pulse rate and must not be used in patients with uncontrolled high blood pressure, as well as by anyone with heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients using a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients on the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

From a psychiatric point of view, evidence points too the ordinary neural mechanism for goal-directed behavior has become hijacked by the addiction, and malfunctions in a way that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus along with the person engages in a "goal-directed behavioral response" that creates a "natural high"(Bostwick & Bucci, 2008).

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