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Experts from Brigham Young University in Utah found out that addiction is a result of an 'overcorrection' within the brain, a PsychCentral report said.

Using two separate drugs to shed pounds can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the those who go through it you ought to err along the side of caution and let the FDA do its job and demand some study be done in order that the public is aware of the side effects and perils associated with the medications before we take them. Keep in mind that drug companies will be in business to generate money and that they would say almost anything to keep people on their own medications.

Researchers discovered that participants investing in this drug for a year, dropped a few pounds within four weeks and have kept the body weight off through the entire 56 weeks of the study. Contrave is a combination in the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which can be made up of several active ingredient, which may make them more effective and safer.

Combo-pilling will be the newest fad or better yet the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular is the fact that by right now there are no long term prescription slimming capsules that have been licensed by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be approved by the FDA.

Seizures are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug also can raise hypertension and heartrate, and must not be used in individuals with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heart rate and must stop used in patients with uncontrolled high blood pressure levels, along with by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients having a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients towards the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.

"This will be the first drug I'm mindful of that targets both the appetite and reward centres inside brain," he said.


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