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A new drug approved for weight-loss through the U.S. Food and Drug Administration had accomplishment in clinical trials, however it isn't a panacea for losing weight. It must be used in combination with a low-calorie diet and frequent exercise in order to be effective.

Using two separate drugs to lose weight can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you should err on the side of caution and let the FDA do its job and demand some research be done so that the public understands the side effects and dangers of the medications before we bring them. Keep in mind that drug companies have been in business to earn money and that they would say anything to keep people on his or her medications.

Researchers discovered that participants investing in this drug for the year, dropped excess weight within one month and have kept the body weight off throughout the 56 weeks of the study. Contrave is really a combination of the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which are made up of several active ingredient, which can make them more effective and safer.

Combo-pilling could be the newest fad or better yet the newest into the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular is the fact that as of right now there aren't any long term prescription weight loss supplements that have been approved by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug can also raise blood pressure level and heartbeat, and mustn't be used in people who have a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise hypertension and heartrate and must not used in patients with uncontrolled high hypertension, as well as by a person with heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients which has a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients for the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

"This may be the first drug I'm aware of that targets both appetite and reward centres in the brain," he said.

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