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Evidence is increasing that addiction without exception is related to problems with the brain's reward center, specially the mesolimbic system. This area of the problem regulates reward responses in establishing food and sex, plus nurturing infants and children. One of the most important neurotransmitters linked to reward responses, both when they malfunction and when they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the amount of dopamine released in responding to a stimulus"(Bostwick & Bucci, 2008).

Using two separate drugs to shed pounds can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight loss and the those who go through it you should err along the side of caution and allow the FDA do its job and demand some study be done so the public recognizes the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to earn money and that they would say almost anything to keep people on the medications.

Researchers found out that participants using this drug to get a year, dropped excess weight within 4 weeks and have kept the load off through the 56 weeks in the study. Contrave is often a combination of the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which might be made up of multiple active ingredient, which may make them more potent and safer.

Combo-pilling will be the newest fad or better yet the newest in the future under scrutiny and thus it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular may be the fact that by right now there aren't any long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures can be a side effect with Contrave and must not be taken in those with seizure disorders. The drug also can raise blood pressure and heartbeat, and shouldn't be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise hypertension and heartrate and must not used in patients with uncontrolled high blood pressure levels, along with by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients for the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation.

BioCorRx, Inc.'s naltrexone implant is no bigger than a thumb and is inserted within the patient's skin by way of a 30-minute, non-invasive outpatient procedure made by a health care professional. The implant is administered in BioCorRx, Inc.'s Start Fresh Program which can be distributed in several states by independent rehabilitation facilities.


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