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The Food and Drug Administration, FDA, has approved the drug Vivitrol for the treatment of opioid dependence as outlined by a news release by them on 10-12-2010.

Using two separate drugs to shed pounds can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you need to err along the side of caution and allow FDA do its job and demand some study be done in order that the public recognizes the side effects and hazards of the medications before we take them. Keep in mind that drug companies have been in business to make money and that they would say everything to keep people on his or her medications.

Researchers discovered that participants using this drug to get a year, lost excess weight within one month and have kept the body weight off throughout the 56 weeks with the study. Contrave is often a combination from the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which might be made up of more than one active ingredient, that might make them more potent and safer.

Combo-pilling may be the newest fad or in addition to this the newest ahead under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is becoming popular may be the fact that at the time of right now there are no long term prescription slimming capsules that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug can also raise blood pressure and heartbeat, and really should not be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise hypertension and heartrate and must stop used in patients with uncontrolled high blood pressure, along with by you are not heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients with a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients for the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.

"There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.

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