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Evidence is increasing that most addiction without exception is related to problems with the brain's reward center, especially the mesolimbic system. This section of the problem regulates reward responses in acquiring food and sex, plus in nurturing infants and children. One of the most important neurotransmitters associated with reward responses, both after they malfunction and whenever they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the amount of dopamine released in in reaction to a stimulus"(Bostwick & Bucci, 2008).

Using two separate drugs to lose weight naturally can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you need to err along the side of caution and allow FDA do its job and demand some research be done so your public is aware of the side effects and risks of the medications before we take them. Keep in mind that drug companies have been in business to earn money and that they would say almost anything to keep people on the medications.

Researchers discovered that participants using this drug for the year, lost weight within 4 weeks and have kept the load off through the entire 56 weeks in the study. Contrave is really a combination of the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs that are made up of many active ingredient, that might make them far better and safer.

Combo-pilling may be the newest fad or better yet the newest to come under scrutiny and so it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills is now popular is the fact that as of right now there are not any long term prescription diet pills that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be licensed by the FDA.

Seizures certainly are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug can also raise blood pressure level and heartrate, and really should not be used in people who have a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure and pulse rate and must 't be used in patients with uncontrolled high hypertension, and also by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients having a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients for the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.

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