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The Food and Drug Administration, FDA, has approved the drug Vivitrol for the treatment of opioid dependence according to a news release by them on 10-12-2010.

Using two separate drugs to shed pounds can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the those who go through it one should err along the side of caution and permit the FDA do its job and demand some research be done in order that the public knows the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies come in business to generate income and that they would say almost anything to keep people on their medications.

Researchers found that participants taking this drug for any year, dropped excess weight within a month and have kept the weight off through the entire 56 weeks from the study. Contrave can be a combination in the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs that are made up of several active ingredient, which can make them more potent and safer.

Combo-pilling is the newest fad or also the newest to come under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular may be the fact that since right now there aren't any long term prescription weightloss pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be authorized by the FDA.

Seizures really are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug can also raise blood pressure levels and heartrate, and must not be used in those with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure and heartbeat and must stop used in patients with uncontrolled high blood pressure levels, in addition to by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients for the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.

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