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It was found out that naltrexone and bupropion combined, which may be marketed later on as Contrave, have better weight loss results than eating and working out alone.

Using two separate drugs to shed pounds can be very effective there are combinations while watching FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you need to err along the side of caution and allow FDA do its job and demand some research be done in order that the public knows the side effects and dangers of the medications before we take them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on their medications.

Researchers found that participants taking this drug to get a year, lost weight within one month and have kept the body weight off through the entire 56 weeks of the study. Contrave can be a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs that are made up of more than one active ingredient, that might make them far better and safer.

Combo-pilling may be the newest fad or even better the newest into the future under scrutiny and so it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is now popular is the fact that since right now there are not any long term prescription diet pills that have been approved by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures certainly are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug could also raise blood pressure level and heartrate, and mustn't be used in people who have a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise hypertension and heartrate and must stop used in patients with uncontrolled high blood pressure level, and also by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.

"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.

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