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It was discovered that naltrexone and bupropion combined, that could be marketed in the future as Contrave, have better weight loss results than eating and working out alone.

Using two separate drugs to lose weight can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with fat loss and the those who go through it one should err to the side of caution and let the FDA do its job and demand some study be done in order that the public knows the side effects and risks of the medications before we bring them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on their medications.

Researchers found that participants using this drug for any year, dropped excess weight within a month and have kept the weight off during the entire 56 weeks from the study. Contrave can be a combination of the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which can be made up of many active ingredient, which might make them more effective and safer.

Combo-pilling will be the newest fad or even better the newest into the future under scrutiny and thus it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is now popular will be the fact that at the time of right now there are not any long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures really are a side effect with Contrave and must not be taken in those with seizure disorders. The drug may also raise hypertension and heartbeat, and must not be used in people who have a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heartrate and must not be used in patients with uncontrolled high blood pressure level, as well as by you are not heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients to the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.

"This may be the first drug I'm aware of that targets the two appetite and reward centres inside brain," he explained.


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