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The Food and Drug Administration, FDA, has approved the drug Vivitrol to the treatment of opioid dependence according to a news release by them on 10-12-2010.

Using two separate drugs to shed pounds can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with fat loss and the people who go through it you ought to err along the side of caution and let the FDA do its job and demand some research be done so that the public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies will be in business to earn money and that they would say everything to keep people on their medications.

Researchers discovered that participants investing in this drug for the year, dropped a few pounds within one month and have kept the load off throughout the 56 weeks of the study. Contrave is really a combination with the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which might be made up of more than one active ingredient, that might make them far better and safer.

Combo-pilling may be the newest fad or even better the newest into the future under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular could be the fact that by right now there aren't long term prescription weight loss supplements that have been authorized by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be approved by the FDA.

Seizures really are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug also can raise blood pressure level and heart rate, and shouldn't be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure and heart rate and must 't be used in patients with uncontrolled high hypertension, along with by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients towards the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.

"This may be the first drug I'm conscious of that targets both appetite and reward centres inside brain," he explained.


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