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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight management in addition to a reduced-calorie diet and physical exercise.

Using two separate drugs to shed weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the people that go through it you need to err to the side of caution and let the FDA do its job and demand some study be done in order that the public understands the side effects and dangers of the medications before we drive them. Keep in mind that drug companies are in business to generate income and that they would say anything to keep people on his or her medications.

Researchers found that participants investing in this drug for the year, lost excess weight within a month and have kept the weight off during the entire 56 weeks of the study. Contrave is a combination with the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs that are made up of multiple active ingredient, which can make them more efficient and safer.

Combo-pilling is the newest fad or better yet the newest into the future under scrutiny and thus it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular could be the fact that since right now there are not any long term prescription weight loss supplements that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures certainly are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug also can raise blood pressure and heartbeat, and mustn't be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure levels and heart rate and must stop used in patients with uncontrolled high hypertension, in addition to by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients which has a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients towards the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.

The most common side effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.


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