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On September 26, UCLA researcher reported the results of a study, which indicated that Asians who are struggling with alcoholism will benefit especially from naltrexone, one of three medications authorized by the U.S. Food and Drug Administration (FDA) for that treatment of alcoholism. Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent possess a particular mutation that produces them more likely to benefit from naltrexone, in comparison with about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director in the UCLA Addictions Laboratory. The findings are still available online ( inside the journal Neuropsychopharmacology and you will be published in an upcoming print edition of the journal.

Using two separate drugs to shed pounds can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you should err along the side of caution and let the FDA do its job and demand some research be done so the public recognizes the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies come in business to generate income and that they would say anything to keep people on their own medications.

Researchers found that participants taking this drug for the year, dropped a few pounds within four weeks and have kept the load off through the entire 56 weeks in the study. Contrave can be a combination in the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs that are made up of multiple active ingredient, that might make them more efficient and safer.

Combo-pilling will be the newest fad or also the newest to come under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular could be the fact that at the time of right now there aren't long term prescription diet pills that have been authorized by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be approved by the FDA.

Seizures are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug may also raise hypertension and heart rate, and really should not be used in people who have a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heartrate and must not be used in patients with uncontrolled high blood pressure level, as well as by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients for the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.

The most common side effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.


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