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It was found that naltrexone and bupropion combined, which might be marketed in the future as Contrave, give better weight loss results than exercise and dieting alone.
Using two separate drugs to shed pounds can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the people that go through it you need to err to the side of caution and permit the FDA do its job and demand some investigation be done in order that the public is aware of the side effects and risks of the medications before we bring them. Keep in mind that drug companies are in business to generate money and that they would say everything to keep people on their own medications.
Researchers discovered that participants using this drug for the year, lost weight within 4 weeks and have kept the load off throughout the 56 weeks with the study. Contrave is often a combination from the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs which are made up of multiple active ingredient, which may make them more efficient and safer.
Combo-pilling may be the newest fad or better yet the newest into the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is now popular is the fact that at the time of right now there are no long term prescription slimming capsules that have been authorized by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be licensed by the FDA.
Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug can also raise hypertension and heart rate, and really should not be used in people who have a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.
The FDA also warned that Contrave can raise hypertension and pulse rate and must not be used in patients with uncontrolled high blood pressure, in addition to by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients having a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients towards the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.
From a psychiatric perspective, evidence suggests that the ordinary neural mechanism for goal-directed behavior may be hijacked with the addiction, and malfunctions such that its ordinary functions are exaggerated and fixated on its object. An object generates a stimulus along with the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).