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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence in accordance with a news release by them on 10-12-2010.

Using two separate drugs to lose weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the people who go through it one should err to the side of caution and allow the FDA do its job and demand some research be done in order that the public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies have been in business to earn money and that they would say almost anything to keep people on his or her medications.

Researchers discovered that participants taking this drug to get a year, dropped excess weight within one month and have kept the body weight off through the 56 weeks of the study. Contrave can be a combination in the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs which might be made up of more than one active ingredient, which may make them more efficient and safer.

Combo-pilling is the newest fad or even better the newest into the future under scrutiny and so it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular may be the fact that since right now there are no long term prescription diet pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be authorized by the FDA.

Seizures really are a side effect with Contrave and must not be taken in those with seizure disorders. The drug also can raise blood pressure levels and heartbeat, and must not be used in individuals with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure and heartbeat and must not used in patients with uncontrolled high hypertension, and also by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients towards the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.

Most of the combinations which are used to enhance weight-loss involve an amphetamine as well as an antidepressant. Phentermine and Prozac really are a popular combination that have been around for some time, and even though it has been around nobody wants to truly combine the 2 and try to get FDA approval to promote it as a weight loss pill. Right there should raise some red flags if the greedy pharmaceutical companies should not be involved in combining medications and selling them something has to be wrong using the combination. In fairness there is certainly one weight reduction combination pill that is certainly in front of the FDA now Contrave?which couples naltrexone, utilized to treat alcohol and substance abuse, with all the antidepressant bupropion (Wellbutrin, Zyban) it's been given the go ahead to move forward by an FDA advisory committee, but by yet hasn't been approved.


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